The increasing burden of pancreatic cancer in Brazil from 2000 to 2019: estimates from the Global Burden of Disease Study 2019.

Data de publicação

2022

Periódico

Revista da Sociedade Brasileira de Medicina Tropical

Resumo

Introduction – Pancreatic cancer is increasing worldwide. The burden of pancreatic cancer in Brazil and its states was analyzed and compared with that from the USA and China.

Methods – This is a descriptive study of the incidence and mortality estimates from the Global Burden of Disease 2019 study, from 2000 to 2019. The Brazilian states presenting the highest and lowest socio-demographic index (SDI) were selected from each of the five regions. The SDI consists of the per capita income, education, and fertility rate of each population.

Results – A significant increase was found in age-standardized incidence and mortality of pancreatic cancer in all three countries, with differences in magnitude and annual increases. In Brazil, this incidence rose from 5.33 [95% Uncertainty Interval (UI): 5.06- 5.51] to 6.16 (95% UI: 5.68- 6.53) per 100,000 inhabitants. China and the Brazilian states with the lowest SDI, such as Pará and Maranhão, showed lower incidence and mortality rates, although presenting the highest annual increases. No difference was found between the sexes. A higher mortality rate was observed for those individuals of 70+ years, which was three to four times higher than those aged 50 to 69 years.

Conclusions – The increasing burden of pancreatic cancer in the studied countries, and the higher estimates for the elderly in a fast-aging country such as Brazil, indicates that more resources and health policies will be necessary. The greatest increase in the states with lower SDI reflects inequalities in the access to diagnosis and registries of this cancer.

DOI/link

https://doi.org/10.1590/0037-8682-0271-2021

Autoria

Vínculo institucional

Lattes

Orcid

Diogo Oliveira Chaves

Faculdade Ciências Médicas de Minas Gerais, Programa de Pós-Graduação em Ciências da Saúde, Belo Horizonte, MG, Brasil.

Aline Cândida Bastos

Faculdade Ciências Médicas de Minas Gerais, Programa de Pós-Graduação em Ciências da Saúde, Belo Horizonte, MG, Brasil.

Alessandra Maciel Almeida

Faculdade Ciências Médicas de Minas Gerais, Programa de Pós-Graduação em Ciências da Saúde, Belo Horizonte, MG, Brasil.

Maximiliano Ribeiro Guerra

Universidade Federal de Juiz de Fora, Programa de Pós-Graduação em Saúde Coletiva, Juiz de Fora, MG, Brasil.

Maria Teresa Bustamante Teixeira

Universidade Federal de Juiz de Fora, Programa de Pós-Graduação em Saúde Coletiva, Juiz de Fora, MG, Brasil.

Ana Paula Souto Melo

Universidade Federal de São João Del Rey, Faculdade de Medicina, Divinópolis, MG, Brasil.

Valéria Maria de Azeredo Passos

Faculdade Ciências Médicas de Minas Gerais, Programa de Pós-Graduação em Ciências da Saúde, Belo Horizonte, MG, Brasil; Universidade Federal de Minas Gerais, Faculdade de Medicina, Belo Horizonte, MG, Brasil.